Colostrum
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Description
Fuel your dog’s health from the inside out.
PupRx Colostrum is a powerful, single-ingredient supplement made from the first milk of grass-fed cows — nature’s original immune defense. Rich in functional nutrients like Immunoglobulin G (IgG), growth factors, and immune peptides, this gently dried powder helps your dog fight off infections, recover faster, and stay balanced from nose to tail.
Whether your pup is dealing with allergies, sensitive digestion, post-vaccine fatigue, or chronic inflammation, this daily scoop offers targeted, natural support without synthetic additives.
With over 100+ bioactive nutrients, including PRPs, lactoferrin, IGF-1, and EGF, this formula supports:
- Immune health
- Gut lining integrity
- Inflammatory response
- Puppy development & senior vitality
Sourced & Made in the USA. Backed by batch-specific testing for IgG content, safety, and purity.
How To Use
Ingredients
The NO List
- No Fillers
- No Flavors
- No Preservatives
- No Artificial Ingredients
- No Gluten
- No Soy
- No GMO's
- No Antibiotics
- No Hormones
- No Colors or Sweeteners
- No Mystery Blends
- No BS — Just 100% Colostrum
Testing
- IgG Content Verification
- Protein & Fat Analysis
- Microbiological Safety Testing
- Heavy Metals Testing
- Organoleptic Testing
Why Colostrum Works Wonders for Dogs
Gut Repair
Colostrum contains growth factors like IGF-1 and TGF-β that help heal the gut lining, reduce inflammation, and restore balance in the digestive tract.
Allergy Relief
By sealing a “leaky gut” and modulating immune response, colostrum can reduce itchy skin, red paws, and food intolerance.
Immune Boosting IgG
Contains at least 25% Immunoglobulin G – antibodies that neutralize harmful bacteria, viruses, and toxins.
Lactoferrin & Antimicrobials
Fights bad bacteria, supports oral health, and naturally helps prevent infections.
Anti-Inflammatory Effects
Helps reduce systemic inflammation, easing joint stiffness and age-related decline.
Post-Illness Recovery
Ideal after antibiotics or illness – replenishes lost gut flora and strengthens resilience.
Research studies on bovine colostrum
Enhanced Immune Response & Vaccine Efficacy
Long-term trial (24 dogs, 40 weeks): Diets supplemented with 0.1% spray-dried bovine colostrum led to significantly higher canine distemper virus (CDV) vaccine-specific IgG levels and increased fecal IgA, alongside more diverse and stable gut microbiota
Supplementary review (2025) by Yu & Satyaraj: Confirms colostrum's immunomodulatory properties, enhancing both mucosal and systemic immunity in dogs
Improved Gut Health & Digestive Stability
Puppy trial (70 puppies): Supplementation (0.5 g daily for 10 days) improved fecal quality during kennel stress compared to skim-milk‑only controls
Adult dogs: Trials observed increased gut microbiota diversity/stability and higher fecal IgA—markers of healthier gut-associated lymphoid tissue (GALT)
Benefits Across Life Stages
Adult dogs: Expanded immune response longevity – 50% higher CDV antibody levels sustained at 6 months post-vaccination.
Puppies: Immunoglobulin-rich colostrum supports gut lining development and helps fill the "immunity gap" after maternal antibodies wane
Support During Stress & Weaning
Weaning puppies: Fecal consistency improved during stressful environmental changes (e.g., arrival at a pet store) pmc.ncbi.nlm.nih.gov
Exercise/challenge stress in adults: Dogs maintained more stable gut microbiomes post-exercise, indicating better stress resilience .
Bioactive Components with Broad Benefits
Contains immunoglobulins (IgG, IgA, IgM), lactoferrin, growth factors (IGF, EGF), and proline-rich polypeptides—all key to immune modulation, gut integrity, and tissue repair
FAQ About Colostrum
What is colostrum, and why is it good for dogs?
Colostrum is the first milk produced by mammals after giving birth. It’s rich in natural immune-supporting compounds like IgG, lactoferrin, and growth factors that help promote gut health, allergy relief, and immune resilience in dogs.
Is colostrum safe for all dogs?
Yes! Colostrum is safe for most dogs, including puppies, seniors, and dogs with sensitive stomachs. If your dog has a known dairy allergy, consult your vet before use.
Will this help my dog with allergies or itchy skin?
Yes, colostrum helps balance your dog’s immune response and can reduce symptoms like itching, paw licking, and seasonal allergy flare-ups over time.
How long does it take to see results?
Some dogs may show improvement in digestion or itching in just a few days. For others, especially with long-term issues, allow at least 4 weeks of daily use to see full benefits.
What are bioactives, IgG, and all these other colostrum terms?
Bioactives are naturally occurring compounds in colostrum that do things inside the body — like support immunity or help cells repair.
- IgG (Immunoglobulin G) is an antibody that helps fight viruses and bacteria.
- Lactoferrin: Supports gut health and helps manage iron levels in the body. It also has natural antimicrobial properties to protect your dog’s digestive tract.
- Growth Factors (IGF, EGF): These aid in tissue repair, cellular regeneration, and gut lining recovery — especially helpful for dogs with inflammation, allergies, or after illness.
- PRPs (Proline-Rich Polypeptides): These smart proteins help regulate your dog’s immune system — calming it when it overreacts (like with allergies) and boosting it when it’s under stress.
Is this the same as probiotics?
No, but it complements them. While probiotics add beneficial bacteria, colostrum supports the immune system, gut lining, and natural microbiome balance from the inside out.
Does it contain lactose?
Only trace amounts. Our colostrum is low-lactose and well-tolerated by most dogs — even those with mild dairy sensitivities.
Can I give it with other supplements or medications?
Yes! Colostrum is a natural whole food and can safely be used alongside most supplements or medications. When in doubt, check with your vet.